Boltz plugin for Codex
Use Boltz from Codex for biomolecular modeling workflows: predict structure and binding for protein, RNA, DNA, and ligand complexes; rank small-molecule or protein libraries against targets; and design novel small molecules, peptides, antibodies, nanobodies, or custom protein binders with structures and confidence metrics.
How to install Boltz in Codex
codex plugin add boltz-api-cli@openai-curatedCommand format from the Codex CLI reference (codex plugin add <plugin[@marketplace]>); openai-curated is the marketplace name in OpenAI's catalog file. You need to be signed in to Codex. Source: Codex CLI reference.
Or in Codex CLI type /plugins and pick it from the OpenAI curated marketplace; in the ChatGPT desktop app, open the Plugins tab. Start a new session afterwards so the plugin's skills and tools load. (OpenAI plugin docs)
What it contains
Skills (8)
boltz-check-status— Boltz job status and result recovery. Use when listing jobs, checking progress, resuming downloads, recovering results, or downloading an existing job ID. Not for starting new jobs.boltz-cli-setup— Boltz CLI setup and auth. Use when installing, updating, verifying, or authenticating `boltz-api`, or fixing missing CLI, PATH, sandbox, browser login, or auth errors.boltz-protein-design— Design new protein binders with Boltz. Use when generating protein, peptide, antibody, nanobody, or custom binder candidates for a target. Not for screening existing proteins or small molecules.boltz-protein-screen— Screen existing protein binders with Boltz. Use when ranking a supplied protein, peptide, antibody, nanobody, or binder library against a target. Not for designing new proteins or screening small molecules.boltz-small-molecule-adme— Predict Tier-1 ADME/ADMET for small molecules with Boltz from bare SMILES — no target, no docking. Use when the user wants solubility, permeability, or lipophilicity/logD for a molecule or list of molecules. Not for ranking molecules against a protein target…boltz-small-molecule-design— Design new small-molecule binders with Boltz. Use when generating novel ligands or hits for a target without a fixed compound library. Not for screening existing molecules or one-off docking.boltz-small-molecule-screen— Screen existing small-molecule libraries with Boltz. Use when docking, scoring, or ranking a supplied SMILES or compound library against a target; also returns free Tier-1 ADME/ADMET (solubility, permeability, lipophilicity/logD) per molecule. Not for de…boltz-structure-and-binding— Predict structures and binding for one defined complex with Boltz. Use when folding a protein, RNA, DNA, or ligand complex, docking one ligand, predicting an interface, or scoring binding. Not for screening libraries or design.
Example prompts from the manifest
- Predict EGFR L858R binding to osimertinib
- Design nanobodies for a SARS-CoV-2 RBD epitope
- Design selective JAK2 binders from Enamine REAL
About this listing
Boltz is in OpenAI's official curated Codex plugin catalog, published by Boltz. It shows up in the Codex CLI plugin browser (/plugins) and in the ChatGPT desktop app's Plugins tab. From its files we found 8 skills. The manifest says version 0.1.1. It's one of 5 listings in the Scientific Research category. It also appears in best Codex plugins for design and UI.
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Boltz FAQ
How do I install Boltz in Codex?
Run codex plugin add boltz-api-cli@openai-curated (format from the Codex CLI reference). Or in Codex CLI type /plugins and pick it from the OpenAI curated marketplace; in the ChatGPT desktop app, open the Plugins tab. Start a new session afterwards so the plugin's skills and tools load.
Is Boltz an official Codex plugin?
Yes. Boltz is in OpenAI's official curated Codex plugin catalog (marketplace openai-curated), published by Boltz. It appears in the Codex CLI plugin browser and the ChatGPT desktop app's Plugins tab.
What does Boltz include?
From its files in OpenAI's plugin repo, Boltz includes 8 skills: boltz-check-status, boltz-cli-setup, boltz-protein-design, boltz-protein-screen, boltz-small-molecule-adme, boltz-small-molecule-design….
Details
- Type
- Plugin
- Category
- Scientific Research
- Source
- Official OpenAI curated
- Publisher
- Boltz
- Version
- 0.1.1
- License
- MIT
- Sign-in
- Asks you to connect/sign in when you install it
- Keywords
- boltz, boltz-api, go-cli, computational-biology, protein-design, protein-screening, small-molecule-design, virtual-screening, structure-prediction, molecular-modeling, drug-discovery, biotech
- Source
- https://github.com/openai/plugins/tree/main/plugins/boltz-api-cli
- Website
- https://boltz.bio
- Listed in
- OpenAI catalog file
- Tested by CodexStacks
- Not yet
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Markdown
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<a href="https://codexstacks.com/p/boltz-api-cli/" style="display:block;max-width:380px;box-sizing:border-box;padding:14px 16px;border:1px solid #3a2c26;border-radius:12px;background:#0d0b0a;color:#f3ece6;font:14px/1.45 -apple-system,Segoe UI,Roboto,Helvetica,Arial,sans-serif;text-decoration:none"><span style="display:block;font-size:16px;font-weight:700;color:#f3ece6">Boltz</span><span style="display:block;margin:2px 0 8px;font-size:12px;color:#b5a9a1">Official Codex plugin · 8 skills</span><span style="display:block;margin:0 0 10px;color:#ddd3cc">Use Boltz from Codex for biomolecular modeling workflows: predict structure and binding for protein, RNA, DNA, and…</span><span style="font-size:12px;font-weight:600;color:#ffb347">View on CodexStacks →</span></a>Markdown summary
**[Boltz on CodexStacks](https://codexstacks.com/p/boltz-api-cli/)**: Official Codex plugin with 8 skills. Install: `codex plugin add boltz-api-cli@openai-curated`More on badges, embeds and keeping your listing up to date: CodexStacks for plugin authors.
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